Our kidneys are very important organs for the body, which work to clean the blood and maintain the balance of fluids in the body. But do you know that some rare kidney diseases are emerging as a secret threat? Studies have shown that patients suffering from these rare kidney diseases have a much higher risk of kidney failure. Let us discuss this topic today.

According to recent research published in The Lancet journal, patients suffering from a rare kidney disease have a higher risk of kidney failure than normal chronic kidney disease (CKD) patients, but their survival rates are better. According to published data, patients with rare kidney disease have a much higher chance of developing kidney failure within 5 years (28%) than do patients with moderate CKD (1%). However, the survival rate of patients suffering from the rare kidney disease was found to be better than that of CKD patients.

What do researchers say?

Dr. Katy Wong and her colleagues from the Department of Nephrology, University College London have done this research. He says that rare diseases are generally suffered by less than 2 lakh people in America and less than 5 out of 10 thousand people in Europe. He further said that there is a need to better understand the progression of these diseases and the kidney and patient survival rates. This may help in exploring the possibilities of new treatments in the future.

27 thousand patients were evaluated.

Researchers conducted an analysis using data from the UK's National Registry of Rare Kidney Diseases. In this study, 27,285 patients suffering from 28 types of rare kidney diseases were evaluated. The study involved 108 UK renal care centers between 2010 and 2022, following patients for an average of 9.6 years. The main goal of the study was to understand the mortality rate and probability of kidney failure.

Researchers found that patients with the rare kidney disease were more likely to develop kidney failure than more than 2.8 million patients with CKD, but had better survival rates. Wong and his team also found that the average age of kidney failure and death (time from diagnosis to death from starting dialysis), the time from diagnosis to eGFR threshold, and the time to treatment vary across rare kidney diseases. Is.

The study concludes

that rare kidney diseases account for 5% to 10% of people with CKD but represent more than 25% of patients receiving kidney replacement therapy. The study concludes that strategies to reduce cardiovascular risk and other causes of death are very important. A large part of kidney risk is due to individual rare kidney diseases. Therefore, patients with rare kidney disease must be distinguished from patients with more common causes of CKD, emphasizing the importance of early specialist referral and diagnosis.

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