After double pneumonia, Pope Francis is at risk of sepsis, this is how it attacks vital organs
- bySherya
- 24 Feb, 2025

Prayers are being offered all over the world for Pope Francis's recovery, but he is still not out of danger. Doctors fear that he may have developed sepsis.

What is Sepsis: 88-year-old Pope Francis is in critical condition due to double pneumonia and severe lung infection. The Vatican has confirmed that he has long-standing respiratory problems related to asthma and is in danger despite being conscious. He is being given high flow oxygen to help him breathe and is undergoing blood transfusion due to low platelet count.
Concerns about sepsis
Doctors fear Pope Francis may have sepsis, a life-threatening condition that occurs when an infection spreads to the bloodstream, potentially leading to organ failure and death. Given his chronic lung issues, Pope Francis is susceptible to respiratory infections, especially in the winter. His initial diagnosis included a complex viral, bacterial and fungal respiratory infection that later turned into pneumonia in both lungs.
Dr. Sergio Alfieri, of Rome's Gemelli Hospital, has focused on the possibility that the primary danger is the possibility of germs entering the bloodstream, which can lead to sepsis. Although there was no evidence of sepsis as of Friday, blood tests on Saturday showed a low platelet count, which could be due to an infection or adverse reaction to medication. Alfieri stressed that if sepsis develops, it would be extremely difficult for Pope Francis to recover, given his age and respiratory complications.
What is sepsis?
Sepsis occurs when the immune system overreacts to an infection, causing damage to healthy tissue and organs. This can lead to severe inflammation, multiple multi-organ failure, and death. If left untreated, sepsis can progress to septic shock, which can cause a severe drop in blood pressure and critical organ damage.
Risk factors and symptoms
Sepsis is more common in older adults (65+), people with chronic diseases (diabetes, cancer, kidney disease), and people with weakened immunity. Hospitalization, severe wounds, catheters, and breathing tubes also increase the risk. Common symptoms include low energy, fever, chills, rapid breathing, confusion, fast heart rate, low blood pressure, and extreme pain.
Long-term complications
Survivors of sepsis may face organ damage, cognitive impairment and mental health issues. Research shows that more than 50% of survivors lose the battle for life within 5 years. Early treatment increases the chances of survival, but those who recover are at higher risk of future infections.
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