Recently, the Cortisol hormone was responsible for the heart attack that Sushmita Sen had and it is a hormone that is responsible for everything from diabetes to blood pressure and clotting. Blood Clotting) is responsible for. An imbalance or high of this hormone becomes fatal. Let's understand how.
Cortisol is a steroid hormone that belongs to the class of glucocorticoid hormones and is made in the adrenal gland. Most cells in the body have cortisol receptors. It is produced in the adrenal glands and regulates the metabolism of the body. Cortisol hormone is responsible for stress and this is the reason why it is also called 'stress hormone'. When this hormone is high, what are the dangers that arise, let us know.
How does cortisol increase diabetes?
The hormone cortisol helps control blood sugar and increase energy levels. But when cortisol and epinephrine are unable to maintain the body's biochemical and hormonal balance, the hormone floods the body with excess glucose to temporarily increase energy levels. During stress, the cortisol hormone taps the glucose in the protein stores with the help of gluconeogenesis in the liver, which inhibits the production of insulin in the body and inhibits the storage of glucose. However, when the level of cortisol in the body increases, the body maintains its normal-insulin resistant state. The continuous production of glucose can lead to high sugar levels and induce diabetes. Due to the high amount of glucose in the body, the risk of type-2 diabetes increases.
How is cortisol responsible for high blood pressure?
Cortisol hormone plays an important role in high blood pressure. Cortisol balances the level of water and sodium in the body, but when this hormone is high, the level of sodium increases and the blood pressure in the arteries increases. Cortisol hormone-induced hypertension is caused by reduced activity of the nitric oxide depressor system which increases the level of ET [10] in the body.
According to researchers, excess cortisol in the body can lead to other forms of high blood pressure, such as pronounced mineralocorticoid and liquorice abuse. High cortisol hormone can increase the serum concentration of the hormone produced by the kidneys and cause inflammation in the body. Apart from this, high blood pressure can also be the cause of chronic renal failure or high blood pressure arising due to a low birth rate.
Diabetes and high blood pressure are the results of increased cortisol levels.
Cortisol hormone is necessary to maintain the flow of blood in the body. However, high cortisol content can increase blood sugar levels and lead to high blood pressure. For diabetes and high blood pressure, increased cortisol levels increase the amount of glucose in the body.
Cortisol releases the hormone insulin and reduces GLP-1 production, thereby regulating the body's insulin levels. Furthermore, over time, an improper balance of the cortisol hormone in the body causes Cushing's syndrome. It can also happen due to the intake of oral corticosteroid medicine for a long time. Common symptoms of the syndrome include a round face, fatty humps between the shoulders, delicate skin that bruises easily, and stretch marks on the skin. Apart from this, Cushing's syndrome can also lead to bone loss, high blood pressure and type-2 diabetes. Â
