Everyone takes various measures to prevent serious diseases like cancer. On the other hand, scientists are continuously doing new research so that better ways of treating and preventing cancer can be found. Recently, a new study has revealed that a popular medicine used in the treatment of diabetes can also reduce the risk of blood cancer.
A new study by Danish researchers has found a link between metformin use and a reduced risk of MPN (myeloproliferative neoplasm), a rare blood cancer. The researchers say several other studies have examined the link between metformin use and risk of solid cancers, and the analysis suggests an increased risk for certain cancers, including cancers of the colorectal, liver, pancreas, stomach and esophagus. There is a reduction of up to 30-55%.
For the study, researchers looked at 3816 cases and 19,080 controls. They found that metformin, a drug used to treat type 2 diabetes, has become so widely used in recent decades that it is now one of the most commonly prescribed drugs in Denmark.
Benefits of metformin
- Reducing the risk of cancer, especially for colorectal, breast and prostate cancer.
- Potentially increasing lifespan by improving cellular health.
- Helping with weight loss and reducing symptoms of polycystic ovary syndrome (PCOS) by regulating periods and improving fertility.
- Increasing heart health by reducing the risk of heart disease.
- Having potential neuroprotective effects, reducing the risk of neurodegenerative diseases such as Alzheimer's.
How does metformin work?
Metformin lowers blood sugar levels by reducing glucose production in the liver. It increases insulin sensitivity, allowing muscle and fat cells to absorb glucose more effectively. Metformin also reduces the absorption of glucose from the intestines. By activating the AMP-activated protein kinase (AMPK) enzyme, it helps control the body's energy balance and cellular metabolism. These combined actions reduce insulin resistance and improve blood sugar control without causing significant weight gain. The multifaceted mechanisms of metformin make it a cornerstone treatment for type 2 diabetes and contribute to its potential benefits in other conditions.
(PC: Freepik)
